WSMH FOX 66 on Facebook WSMH FOX 66 Twitter WSMH FOX 66 RSS Feed WSMH FOX 66 Mailing List
 

FOX 66 News at Ten

WSMH FOX 66 :: News - News at Ten - Studies show big promises for HIV prevention shot
Studies show big promises for HIV prevention shot

Story by Marilynn Marchione / ASSOCIATED PRESS

Exciting research
suggests that a shot every one to three months may someday give an
alternative to the daily pills that some people take now to cut their
risk of getting HIV.

The experimental drug has only been tested
for prevention in monkeys, but it completely protected them from
infection in two studies reported at an AIDS conference on Tuesday.

"This
is the most exciting innovation in the field of HIV prevention that
I've heard recently," said Dr. Robert Grant, an AIDS expert at the
Gladstone Institutes, a foundation affiliated with the University of
California, San Francisco.

"Both groups are showing 100 percent
protection" with the drug, Grant said of the two groups of researchers.
"If it works and proves to be safe, it would allow for HIV to be
prevented with periodic injections, perhaps every three months."

Until
a vaccine is developed, condoms are the best way to prevent infection
with the AIDS virus and many other sexually spread diseases. But not
everyone uses them, or does so all the time, so public health officials
have pursued other prevention options.

A drug used to treat
people with HIV — Gilead Science's Truvada — also is used to help
prevent infection in people who don't have the virus. A big study in gay
men a few years ago found it could cut this risk by up to 90 percent,
depending on how faithfully people take the daily pills.

The new
research tested something that could make this type of prevention much
more practical — a long-acting experimental drug made by GlaxoSmithKline
PLC. The studies tested it in macaques exposed to a human-monkey
version of HIV.

Researchers at the Centers for Disease Control
and Prevention gave six monkeys shots of the drug every four weeks; six
others got dummy shots. All were exposed to the virus twice a week for
11 weeks.

The monkeys who got the fake treatment were readily
infected "but the animals that received the long-acting drug remained
protected," said study leader Gerardo Garcia-Lerma of the CDC.

The
results mirror what was seen in the CDC's early research in monkeys on
Truvada, the pill that's available for HIV prevention now.

In the
second study, Chasity Andrews and others at the Aaron Diamond AIDS
Research Center at Rockefeller University in New York gave eight monkeys
two shots of the drug, four weeks apart, and dummy shots to eight
others. The animals were exposed to the virus weekly for eight weeks.
Again, all animals given the fake treatment were quickly infected and
those on the drug were all protected.

To see how long a single
shot would last, they did a second study. The single shot protected 12
monkeys for about 10 weeks on average.

The dose used in a single shot corresponded to what people would get from a shot every three months, researchers said.

"This
is really promising," said Dr. Judith Currier, an infectious disease
specialist at the University of California, Los Angeles. The research
"supports moving this forward" into human testing, she said.

Currier
is on the program committee for the meeting in Boston where the studies
were presented — the Conference on Retroviruses and Opportunistic
Infections. The New York study also was published online by the journal
Science.

Grant said the long-acting drug is chemically similar to
certain AIDS medicines sold now that are "extremely safe, well
tolerated and extremely potent." A mid-stage trial testing the
long-acting shots in people as a treatment, not a prevention, is already
underway, he said.Studies show big promises for HIV prevention shot

Wednesday, March 5 2014, 09:18 AM EST

National News Headlines

FAA shrinks Washington's no-drone zone
Drones and model aircraft can return to the skies in the outer ring of special airspace around the nation's capital.

Former NYC Ballet principal dancer Violette Verdy, 82, dies
Indiana University says Violette Verdy, a distinguished professor who was principal dancer for New York City Ballet for 20 years and former artistic director of the Paris Opera Ballet and Boston Ballet, has died.

Black Lives Matter activist kills self outside Ohio Statehouse, police say
A community activist connected to the Black Lives Matter movement committed suicide outside the Ohio Statehouse in Columbus Monday night, according to the Columbus Dispatch.

Bergdahl case delayed over classified information dispute
The U.S. Army Court of Criminal Appeals has temporarily halted the desertion case against Sgt. Bowe Bergdahl, who walked off an outpost in Afghanistan in 2009, while it considers a dispute between the sides about how to handle classified information.

Man accused of Wisconsin Masonic temple plot pleads not guiilty
A federal prosecutor handed over hundreds of hours of audio recordings Tuesday to an attorney defending a man accused of plotting to shoot up a Milwaukee Masonic temple in the name of Islam.

Indiana State Museum unveils mallet tied to Abraham Lincoln
A wooden mallet inlaid with the initials "A.L" was made by Abraham Lincoln, who used it during his Indiana youth to make furniture, Indiana State Museum officials said Tuesday in unveiling the artifact that had been a family's secret heirloom for five generations.

Martin Shkreli sued by artist over Wu-Tang Clan album
A Long Island artist has sued ex-pharmaceutical CEO Martin Shkreli and others over use of his art in a Wu-Tang Clan album.

Judge's error could set man free without trial for murder
A mistake by a superior court judge may set a Georgia man free without him ever having to stand trial.

Emanuel AME Church Nominated for Nobel Peace Prize
A group of politicians from Illinois nominated the Emanuel AME Church of Charleston, South Carolina, where nine people were brutally gunned down during a Bible study last June, for a Nobel Peace Prize.

Cleric arrested during Ferguson protest acquitted
A cleric arrested during a protest in Ferguson has been found not guilty of willfully disobeying a police order to disperse.

Officer injured in shootout with Boston Marathon bombers to retire
A transit police officer who was shot and critically wounded during a gun battle between police and the Boston Marathon bombers announced his retirement Tuesday, citing the lingering effects of his injuries.

Joel Osteen Tells Believers: 'Quit Being Against Yourself'
A new book by Lakewood megachurch Pastor Joel Osteen reminds readers that words have power, and aims to help people kick the habit of speaking negatively and to invite good things through the power of the tongue.

Most 'Churchless' US City Inspires Gospel Movement Using Church Network
Churches throughout the San Francisco Bay Area were mostly individual assemblies that were disconnected from one another. The Transforming the Bay With Christ initiative hopes to change all that.

New England digs out from latest storm; snow falls in Mid-Atlantic
A wind-driven winter storm that brought blizzard conditions to Cape Cod fell short of forecast snowfall totals and spared the Northeast the widespread power outages that had been predicted.

California farmers reap record sales in record drought
A new state report shows California farmers reaping record sales despite the drought.

Pastor's widow: Daughters must live without 'sense of fear'
The widow of a pastor slain with eight others at a historic South Carolina church says shielding her young daughters will be a priority during an upcoming murder trial expected to reopen emotional wounds.

Connecticut trooper shot to death during Texas hunting trip
Connecticut State Police say a veteran trooper has been shot to death during a hunting trip in Texas.

Iowa college to hire shooting coach despite alumni objection
An Iowa college is sticking with its decision to hire a full-time coach for its shooting sports club, despite opposition from alumni and others who say guns have no place on the liberal arts school's campus.

Animal hospital owners arrested on drug trafficking charges
The owners of a North Carolina animal hospital were arrested Monday on drug trafficking charges, investigators say.

4 arrested after driver shot in car on Los Angeles street
A man was found shot to death early Tuesday inside a bullet-riddled car at a Los Angeles intersection, and four suspected gang members were later arrested after a police pursuit on two freeways, authorities said.

News at Ten Stories

Advertise with us!
IE6 Float Fix