FOX 66 News at Ten
Story by Marilynn Marchione / ASSOCIATED PRESS
suggests that a shot every one to three months may someday give an
alternative to the daily pills that some people take now to cut their
risk of getting HIV.
The experimental drug has only been tested
for prevention in monkeys, but it completely protected them from
infection in two studies reported at an AIDS conference on Tuesday.
is the most exciting innovation in the field of HIV prevention that
I've heard recently," said Dr. Robert Grant, an AIDS expert at the
Gladstone Institutes, a foundation affiliated with the University of
California, San Francisco.
"Both groups are showing 100 percent
protection" with the drug, Grant said of the two groups of researchers.
"If it works and proves to be safe, it would allow for HIV to be
prevented with periodic injections, perhaps every three months."
a vaccine is developed, condoms are the best way to prevent infection
with the AIDS virus and many other sexually spread diseases. But not
everyone uses them, or does so all the time, so public health officials
have pursued other prevention options.
A drug used to treat
people with HIV — Gilead Science's Truvada — also is used to help
prevent infection in people who don't have the virus. A big study in gay
men a few years ago found it could cut this risk by up to 90 percent,
depending on how faithfully people take the daily pills.
research tested something that could make this type of prevention much
more practical — a long-acting experimental drug made by GlaxoSmithKline
PLC. The studies tested it in macaques exposed to a human-monkey
version of HIV.
Researchers at the Centers for Disease Control
and Prevention gave six monkeys shots of the drug every four weeks; six
others got dummy shots. All were exposed to the virus twice a week for
The monkeys who got the fake treatment were readily
infected "but the animals that received the long-acting drug remained
protected," said study leader Gerardo Garcia-Lerma of the CDC.
results mirror what was seen in the CDC's early research in monkeys on
Truvada, the pill that's available for HIV prevention now.
second study, Chasity Andrews and others at the Aaron Diamond AIDS
Research Center at Rockefeller University in New York gave eight monkeys
two shots of the drug, four weeks apart, and dummy shots to eight
others. The animals were exposed to the virus weekly for eight weeks.
Again, all animals given the fake treatment were quickly infected and
those on the drug were all protected.
To see how long a single
shot would last, they did a second study. The single shot protected 12
monkeys for about 10 weeks on average.
The dose used in a single shot corresponded to what people would get from a shot every three months, researchers said.
is really promising," said Dr. Judith Currier, an infectious disease
specialist at the University of California, Los Angeles. The research
"supports moving this forward" into human testing, she said.
is on the program committee for the meeting in Boston where the studies
were presented — the Conference on Retroviruses and Opportunistic
Infections. The New York study also was published online by the journal
Grant said the long-acting drug is chemically similar to
certain AIDS medicines sold now that are "extremely safe, well
tolerated and extremely potent." A mid-stage trial testing the
long-acting shots in people as a treatment, not a prevention, is already
underway, he said.
Wednesday, March 5 2014, 09:18 AM EST
National News Headlines
|4 teens arrested in alleged shooting plot at high school|
|Four teenagers have been arrested after detectives uncovered an alleged plot to shoot students and teachers at their Northern California high school.|
|Arizona authorities investigating freeway shooting in suburb|
|Authorities are investigating whether a drive-by shooting on a metro Phoenix freeway is related to a string of recent shootings or is an isolated incident.|
|New York mother accused of contaminating son's feeding tube at Ohio hospital|
|A New York mother is accused of putting something dangerous in her 4-year-old son's feeding tube while he was being treated for a rare disease at an Ohio hospital.|
|Witnesses say Oregon gunman handed something to student to give to authorities|
|The 26-year-old gunman who killed fellow students at an Oregon community college spared a student and gave the “lucky one” something to deliver to authorities, according to the mother of a student who witnessed the rampage.|
|Mormon church selects 3 new leaders, all from Utah|
|The Mormon church didn't go far to select three new members for a top governing body that sets policy and runs the worldwide faith's business operations — choosing two former business executives and a cardiologist from Utah who had already been serving in lower church leadership positions.|
|Schools boss faces probe for allegedly barging into home on residency check|
|A superintendent is being investigated for claims he entered a teen student’s home without authorization.|
|25 hurt in collapse of concrete awning at NC school, official says|
|At least 25 people were injured on Saturday night when a concrete canopy collapsed on a group of band students who had gathered outside a North Carolina high school shortly before a competition.|
|Four killed in South Carolina plane crash from Indiana|
|A former top racecar driver was among four Indiana men who died in a plane crash while traveling to the Notre Dame-Clemson football game.|
|Sheriff: Gunman who killed 9 at Oregon college committed suicide|
|The gunman who opened fire at a rural Oregon community college, killing a teacher and eight students, committed suicide after an exchange of gunfire with officers, authorities said Saturday.|
|FBI joins search for Ohio toddler reported missing by family|
|A sheriff in northeastern Ohio says state and federal officers are joining in the search for a toddler whose family says the little girl wandered away while staying at her great-grandmother's house.|